The Role of Coronary Sinus Reducer Devices in Patients with Refractory Angina

21/03/24

Take Home Messages
In the UK, angina affects 3-4% of the adult population with 20,000 new cases each year. Refractory angina leads to significant disability, limited quality of life, multiple medications, and frequent hospital admissions. The Coronary Sinus Reducer device is implanted percutaneously into the coronary sinus and creates a controlled narrowing of the lumen which leads to an increase in pressure in the coronary sinus and hence improves perfusion to ischaemic territories of the myocardium. This device is a potentially safe, efficient and cost-effective solution for patients with refractory angina when standard of care treatment with anti-angina medication and revascularisation fails.

Take Home Messages

In the UK, angina affects 3-4% of the adult population with 20,000 new cases each year. Refractory angina leads to significant disability, limited quality of life, multiple medications, and frequent hospital admissions.
The Coronary Sinus Reducer device is implanted percutaneously into the coronary sinus and creates a controlled narrowing of the lumen which leads to an increase in pressure in the coronary sinus and hence improves perfusion to ischaemic territories of the myocardium.
This device is a potentially safe, efficient and cost-effective solution for patients with refractory angina when standard of care treatment with anti-angina medication and revascularisation fails.

Introduction

Ischaemic heart disease is a leading cause of death worldwide and stable angina is the commonest symptomatic manifestation affecting 112 million people (1, 2). In the UK, angina affects 3-4% of the adult population with 20,000 new cases each year (3). The majority of these patients improve symptomatically with interventions such as percutaneous coronary intervention (PCI) or coronary artery by-pass graft surgery (CABG) (4,32). However, there is a group of patients with refractory angina who are increasingly challenging to manage in clinical practice (4).

The Role of Coronary Sinus Reducer Devices in Patients with Refractory Angina

Introduction

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